| Product Name | Blood Group B antigen antibody [HEB-29] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [HEB-29] to Blood Group B AntigenBlood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens. |
| Immunogen | Mixture of erythrocytes of blood group B and glycoprotein fraction isolated from the saliva of secretors with blood group B. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgM |
| Clone Number | HEB-29 |
| Host Species | Mouse |
| Tested Applications | EIAIHC-PTLCFunctional Assay |
| For IHC-P: Use at an assay dependant dilution. Suitable for use in agglutination. In agglutination tests, the minimum titre is 1:128 with erythrocytes of blood group B. Optimal dilutions/concentrations should be determined by the end user. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Target | Blood Group B antigen |
|---|---|
| Tissue Specificity | This antibody recognizes human blood group B antigens. The specifity of the antibody HEB-29 was confirmed by comparison of specifity and reactivity to standard reagent using >5.000 samples of blood. |
| Application Notes | For IHC-P: Use at an assay dependant dilution. Suitable for use in agglutination. In agglutination tests, the minimum titre is 1:128 with erythrocytes of blood group B. Optimal dilutions/concentrations should be determined by the end user. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | Tissue culture supernatant |
