Mouse monoclonal antibody [10F4B4] to BMP4The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein. [provided by RefSeq, Jul 2008]
Immunogen
The immunogen corresponding to human BMP4 expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
10F4B4
Host Species
Mouse
Tested Applications
ELISAWB
ELISA: 1/10000.
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
ZYME , BMP2B1 , MCOPS6 , BMP2B , OFC11
Target
BMP4
Molecular Weight(MW)
64 kDa (note)
Application
Application
Western blot analysis using BMP4 mAb against BMP4-hIgGFc transfected HEK293 cell lysate.
Application Notes
ELISA: 1/10000.
Additional Information
Form
Liquid
Storage Instructions
Store at 4℃, for long term storage, store at -20℃.