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BMPR1A antibody

Catalog Number:OM241736
OM241736
Discount Price
OM241736-100ul
1~2 Week
100ul
OM241736-50ul
50ul
1~2 Week
Product Profile
Product Name BMPR1A antibody
Antibody Type Primary Antibodies
Product description Mouse Monoclonal Antibody [4B7B2] to BMPR1AThe bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq, Jul 2008]
Immunogen The immunogen corresponding to a region within amino acids 179 and 378 of human BMPR1A expressed in E. Coli.
Conjugation Agarose
Modification Acetylated
Key Feature
Clonality Monoclonal
Isotype IgG1
Clone Number 4B7B2
Host Species Mouse
Tested Applications ELISAFACSICC/IFIHCIHC-PWB
WB:1:500~1:2000
ICC/IF:1:100~1:500
IHC:1:50~1:200
ELISA:1:5000~1:20000
FACS:1:200~1:500
Species Reactivity HumanMouse
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms CD292
ALK3
ACVRLK3
SKR5
10Q23DEL
Target BMPR1A
Molecular Weight(MW) 60 kDa (note)
Application

Application

ELISA analysis of control antigen and antigen using BMPR1A antibody [4B7B2].

Application

WB analysis of human BMPR1A recombinant protein using BMPR1A antibody [4B7B2].

Application

WB analysis of (1) PC-3, (2) K562 and (3) mouse liver lysates using BMPR1A antibody [4B7B2].

Application

WB analysis of lysates from (1) untransfected and (2) BMPR1A (a.a. 179-378)-hIgGFc transfected HEK293 cells using BMPR1A antibody [4B7B2].

Application

IHC-P analysis of colon cancer tissues using BMPR1A antibody [4B7B2].

Application

IHC-P analysis of kidney tissues using BMPR1A antibody [4B7B2].

Application

FACS analysis of HeLa cells using BMPR1A antibody [4B7B2] (green) or a negative control (purple).
Application Notes WB:1:500~1:2000
ICC/IF:1:100~1:500
IHC:1:50~1:200
ELISA:1:5000~1:20000
FACS:1:200~1:500
Additional Information
Form Liquid
Storage Instructions 4°C; -20°C for long term storage
Storage Buffer Ascitic fluid containing 0.03% sodium azide.
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