| Product Name | BMPR1A antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [8L7] to BMPR1AThe bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq, Jul 2008] |
| Immunogen | Recombinant hu-ALK3 extra cellular domain |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | 8L7 |
| Host Species | Mouse |
| Tested Applications | IHCWB |
| WB(1:100-1000)|IHC(1:50-200): |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | bone morphogenetic protein receptor type IA SKR5 ACVRLK3 BMPR1A 10q23del CD292 |
|---|---|
| Target | BMPR1A |
| Tissue Specificity | This antibody was selected for its ability to detect human ALK3. No cross reactivity was found to ALK6 (BMPR-IB). |
| Application Notes | WB(1:100-1000)|IHC(1:50-200): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
