Immunohistochemical analysis of paraffin-embedded human normal myocardium, showing cytoplasmic localization using anti-BNP3 antibody with DAB staining.
Mouse monoclonal antibody [3A6F7C7] to BNPThis gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Jul 2008]
Immunogen
The immunogen corresponding to human BNP, conjugated to KLH.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3A6F7C7
Host Species
Mouse
Tested Applications
ELISAIHCIHC-P
ELISA: 1/10000.
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
NPPB
Target
BNP
Application
Application
Immunohistochemical analysis of paraffin-embedded human normal myocardium, showing cytoplasmic localization using anti-BNP3 antibody with DAB staining.
Application Notes
ELISA: 1/10000.
Additional Information
Form
Liquid
Storage Instructions
Store at 4℃, for long term storage, store at -20℃.