Mouse monoclonal [15C8] to CEBPAThe protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
Immunogen
Synthetic peptide: MESADFYEVEPRPP, corresponding to amino acids 1-14 of Mouse CEBPA.
Key Feature
Clonality
Monoclonal
Isotype
IgG
Clone Number
15C8
Host Species
Mouse
Tested Applications
ICC/IF,IP,WB
WB: 2 ug/ml Optimal dilution / concentration should be determined by the end user.
Species Reactivity
Human,Mouse,Rat
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)