Mouse Monoclonal antibody to C/EBP betaThe C/EBP (CCAAT/enhancer binding protein) family of transcription factors--alpha, beta, delta, and epsilon)--are widely expressed proteins found in a variety of tissues.? These domains contain an evolutionarily conserved five-amino acid motif (the regulatory domain motif RDM) that conforms to the consensus sequence (I/V/L) KXEP.? One of the major roles of these transcription factors is that of metabolic regulation in liver and fat cells.? Studies suggest that these transcription factors act in a cascade aiding in the development of the adipose cell. Three C/EBP beta isoforms (LAP*, LAP, and LIP) arise from different translation initiation and display different function in gene regulation.? From a neurological standpoint, C/EBPs have been implicated in the mediation of nerve growth factor, altering synaptic plasticity, and mediation of inflammatory response in AD patients.
Immunogen
Recombinant mouse LIP.
Key Feature
Clonality
Monoclonal
Isotype
IgG
Clone Number
1H7
Host Species
Mouse
Tested Applications
ICC/IF,IP,WB,ChIP
ICC/IF: 4 ug/ml
Species Reactivity
Mouse,Rat
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
CRP2, Nfil6, 12608, LAP, IL6DBP, IL-6DBP, CEBPB, NF-M, NF-IL6, NFM, NF M, NF IL6, IL 6DBP
Target
C/EBP beta
Application
Application
Western blot of the 3T3-L1 cell lysate using
Application
Immunofluorescence staining of CEBP beta in P388D1 cells using
Application Notes
ICC/IF: 4 ug/ml
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
PBS containing 1 mg/ml BSA and 0.05% sodium azide.