| Product description |
Rabbit polyclonal to C3a ReceptorC3a is an anaphylatoxin generated through activation of the complement C3, and is a potent chemoattractant for phagocytes, and stimulates chemotaxis and other leukocyte functions. C3a binds to eosinophils, basophils, neutrophils, and differentiated U937 cells, that all express receptors forC3a on their cell surface. The C3a receptor has been cloned and shown to be a G protein-coupled receptor with seven putative transmembrane domains (ref 1,2). This receptor is characterized for its large extracellular loop between the fourth and fifth transmembrane domains (ref 3). The loop can be readily detected using the rabbit anti-C3a receptor antibody. |