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Calpain S1 antibody

Catalog Number:OM242828
OM242828
Discount Price
OM242828-100ul
1~2 Week
100ul
OM242828-50ul
50ul
OM242828-20ul
20ul
1~2 Week
Product Profile
Product Name Calpain S1 antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to Calpain S1This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Immunogen Recombinant protein of human CAPNS1
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHCIHC-PWB
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200:
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms 30K
calpain small subunit 1
CAPN4
CDPS
CALPAIN4
CAPNS1
CANPS
CANP
CSS1
Target Calpain S1
Application

Application

Western blot analysis of extracts of various cell lines, using CAPNS1 antibody.

Application

Immunohistochemistry of paraffin-embedded human esophageal cancer using CAPNS1 antibody at dilution of 1:100 (x40 lens).

Application

Immunohistochemistry of paraffin-embedded human colon using CAPNS1 antibody at dilution of 1:100 (x40 lens).

Application

Immunohistochemistry of paraffin-embedded human liver cancer using CAPNS1 antibody at dilution of 1:100 (x40 lens).
Application Notes WB: 1:500 - 1:2000. IHC: 1:50 - 1:200:
Additional Information
Form Liquid
Storage Instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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