| Product Name | CaMKII alpha (phospho Thr286) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to CaMKII alpha (phospho Thr286)CaMKII is a member of calcium/calmodulin-activated kinase, functioning in neural synaptic stimulation and T-cell receptor signaling. CaMKII has catalytic and regulatory domains. The binding of Ca++/calmodulin to its regulatory domain releases its autoinhibitory effect and activates the kinase. The activated CaMKII further autophosphorylates itself at Thr286 to render the kinase constitutively active. |
| Modification | p-Thr286 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Western blotting at 1:500-1:1000. However, the optimal concentrations should be determined individually. The anti-Phospho-CaMKII antibody recognizes only the phosphorylated CaMKII (Thr286) in samples from human, mouse, and rat origins.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | phosphoCaMKII (pT286) CAMK2A phospho-CaMKII (pT286) phosphoCaMKII (pThr286) phospho CaMKII (pThr286) phospho CaMKII (pT286) EC2.7.11.17 KIAA0968 CAMKA phospho-CaMKII (pThr286) EC 2.7.11.17 CaMKII (phospho T286) CaMKII (phospho Thr286) CaMKII ( |
|---|---|
| Target | CaMKII (phospho Thr286) |
| Tissue Specificity | This antibody is specific for CaMKII (phospho Thr286). |
| Cellular Localization | Postsynaptic lipid rafts. |
| Application Notes | Western blotting at 1:500-1:1000. However, the optimal concentrations should be determined individually. The anti-Phospho-CaMKII antibody recognizes only the phosphorylated CaMKII (Thr286) in samples from human, mouse, and rat origins.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | The antibody solution should be gently mixed before use. Store at +4C. Product should remain stable for at least 12 months. |
| Storage Buffer | PBS (pH 7.2) containing 50% glycerol, 1% BSA, and 0.02% thimerosal |
