Application
Western blot analysis of extracts of various cell lines, using CARD11 antibody.Application
Immunofluorescence analysis of A549 cell using CARD11 antibody. Blue: DAPI for nuclear staining.Application
Immunohistochemistry of paraffin-embedded human liver injury using CARD11 antibody at dilution of 1:100 (x40 lens).| Product Name | CARD11 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to CARD11The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008] |
| Immunogen | Recombinant protein of human CARD11 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCIHC-PWB |
| WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | caspase recruitment domain family member 11 BIMP3 CARMA1 |
|---|---|
| Target | CARD11 |
Application
Western blot analysis of extracts of various cell lines, using CARD11 antibody.
Application
Immunofluorescence analysis of A549 cell using CARD11 antibody. Blue: DAPI for nuclear staining.
Application
Immunohistochemistry of paraffin-embedded human liver injury using CARD11 antibody at dilution of 1:100 (x40 lens).| Application Notes | WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
