Mouse monoclonal antibody [S56A-50] to CASKMultidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TRB1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins, and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1.
Immunogen
Fusion protein amino acids 318-415 of rat CASK/Lin2
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
S56A-50
Host Species
Mouse
Tested Applications
IHCIPWB
We recommend a working dilution of 1:1000 (WB).:
Species Reactivity
HumanMouseRatZebra FishXenopus
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Protein G
Target Information
Target
CASK
Molecular Weight(MW)
100kDa (note)
Application
Application
IHC ImageIHC analysis of Pan-KChiP using , tested on mouse cerebellum tissues.
Application
WB ImageWestern blot analysis on rat brain membrane tissues using a 1:1000 dilution of
Application Notes
We recommend a working dilution of 1:1000 (WB).:
Additional Information
Form
Liquid
Storage Instructions
Aliquot and store at -20 C. Avoid repeated freeze-thaw cycles.