Rabbit polyclonal antibody to Caspase 11Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-11 is also synthesized as inactive pro-enzyme that are processed in cells undergoing apoptosis or inflammation. The processed form of caspase-11 consists of large and small subunits which associate to form an active enzyme.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
Western blotting (0.5-4 µg/ml). The antibody detects procaspase-11 (45 kDa), a partially cleaved fragment (30 kDa) and fully cleaved fragment (20 kDa). A 58 kDa unknown identity band was also detected in 3T3 cells.:
Species Reactivity
MouseRat
Concentration
0.2mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
ICH3 CASP-11 ICEB CASP11 ICH-3 Caspase11 ICH 3 CASP 11
Target
Caspase 11
Tissue Specificity
This antibody is specific for Caspase-11.
Application
Application
Western blot analysis of Caspase 11 with 3T3 cell lysate.
Application Notes
Western blotting (0.5-4 µg/ml). The antibody detects procaspase-11 (45 kDa), a partially cleaved fragment (30 kDa) and fully cleaved fragment (20 kDa). A 58 kDa unknown identity band was also detected in 3T3 cells.:
Additional Information
Form
Liquid
Storage Instructions
The antibody solution should be gently mixed before use. Stored at -20 °C for future use.