| Product Name | Caspase 2L antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to Caspase 2LCaspase-2 (also designated Nedd-2/ICH-1) can be alternatively spliced to produce two distinct Caspase-2 mRNA species. One mRNA species encodes a protein of 435 amino acids in length and the mRNA splice variant encodes a 312 amino acid protein. The larger protein, Caspase-2L, in an over expressed state, leads to programmed cell death. Conversely the over expression of Caspase-2S protein, a truncated version of Caspase-2L, has been shown to suppress cell death induced by serum deprivation (5). |
| Immunogen | Synthetic peptide (Human) (C terminal). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-FIHC-PIPWB |
| IHC-F:1:10~1:20 IHC-P:1:10~1:50 IP:1:20~1:100 WB:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 0.2mg/ml |
| Gene Synonyms | CASP-2 ICH-1L ICH-1S ICH1 NEDD-2 NEDD2 CASP 2 ICH 1L ICH 1S NEDD 2 CASP2 ICH1L ICH1S |
|---|---|
| Target | Caspase 2L |
| Tissue Specificity | Reacts with caspase-2L p12 subunit |
| Positive Control | HL-60 and Jurkat |
|---|---|
| Application Notes | IHC-F:1:10~1:20 IHC-P:1:10~1:50 IP:1:20~1:100 WB:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Store this product at 4 °C, do not freeze. The product is stable for one year from the date of shipment. |
| Storage Buffer | PBS with 0.1% sodium azide |
