| Product Name | Anti-Caspase-2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | CASP2 |
|---|---|
| Gene Synonyms | CASP-2 ICH-1 ICH1 MRT80 NEDD-2 NEDD2 PPP1R57 |
| Gene Full Name | caspase 2 |
| Gene Summary | This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011] |
| Alternative Names | CASP-2 CASP2 caspase 2 apoptosis-related cysteine peptidase ICH-1 protease ICH-1L ICH-1L/1S neural precursor cell expressed developmentally down-regulated protein 2 protease ICH-1 protein phosphatase 1 regulatory subunit 57 |
| Molecular Weight(MW) | 50kDa |
| Source | Rabbit |
| Cellular Localization | cytoplasm;cytosol;endopeptidase complex;mitochondrion;nucleolus;nucleus;Complete GO annotation on QuickGO |
| SwissProt ID | P42575 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300. |
