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OM683686
Discount Price
OM683686-100ul
100ul
Product Profile
Product Name Anti-Phospho-Caspase 2 (Ser340) antibody
Antibody Type Primary Antibodies
Immunogen Synthetic peptide conjugated with KLH.
Modification p-Ser340
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CASP2
Gene Synonyms CH1
MRT80
NEDD2
CASP-2
NEDD-2
PPP1R57
Gene Full Name caspase 2
Gene Summary This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Alternative Names CASP 2
CASP-2
Casp2
CASP2_HUMAN
Caspase 2
Caspase 2 apoptosis related cysteine peptidase
Caspase-2 subunit p12
Caspase2
ICH 1
ICH 1 protease
ICH 1L
ICH1
ICH1 protease
ICH1L
NEDD-2
NEDD2
Neural precursor cell expressed developmentally down-regulated protein 2
PPP1R57
Protease ICH-1
Protein phosphatase 1 regulatory subunit 57
Molecular Weight(MW) 51 kDa
Database Links
SwissProt ID P42575
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.
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