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Caspase-2 Rabbit monoclonal antibody

Catalog Number:OM645150
OM645150
Discount Price
OM645150-100ul
100ul
OM645150-50ul
50ul
Product Profile
Product Name Caspase-2 Rabbit monoclonal antibody
Antibody Type Primary Antibodies
Immunogen A synthesized peptide derived from human Caspase-2.
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Rabbit
Tested Applications ICC/IFIHCWB
WB:1:500-1:2000
IHC:1:50-1:200
ICC/IF:1:50-1:200
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CASP2
Gene Synonyms ICH1
MRT80
NEDD2
CASP-2
NEDD-2
PPP1R57
Gene Full Name caspase 2
Gene Summary This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Molecular Weight(MW) 48kDa 30kDa
Cellular Localization cytoplasm,cytosol,nucleus.
Application

WB

Western blot analysis of Caspase-2 expression in Jurkat cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded mouse testis, using Caspase-2 Antibody.

ICC/IF

Immunofluorescent analysis of Hela cells, using Caspase-2 Antibody.
Application Notes WB:1:500-1:2000
IHC:1:50-1:200
ICC/IF:1:50-1:200
Additional Information
Form Liquid
Storage Instructions Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Storage Buffer 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
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