Application
Western blot analysis of extracts from 293/A549/JurKat cells, treated with etoposide 25uM 1h, using CATD (heavy chain,Cleaved-Leu169) Antibody. The lane on the right is treated with the synthesized peptide.| Product Name | Cathepsin D (cleaved Leu169) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to CATD (cleaved Leu169)Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CATD. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| ELISA: 1:40000Optimal dilutions should be determined experimentally by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CATD MGC2311 CPSD CLN10 CATD (cleaved L169) CATD (cleaved Leu169) CATD cleaved L169 CATD cleaved Leu169 Cleaved CATD (L169) Cleaved CATD (Leu169) |
|---|---|
| Target | CATD |
| Molecular Weight(MW) | 27 kDa (note) |
| Tissue Specificity | CATD (heavy chain,Cleaved-Leu169) Antibody detects endogenous levels of fragment of activated CATD resulting from cleavage adjacent to Leu169. |
| Cellular Localization | Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Application
Western blot analysis of extracts from 293/A549/JurKat cells, treated with etoposide 25uM 1h, using CATD (heavy chain,Cleaved-Leu169) Antibody. The lane on the right is treated with the synthesized peptide.| Application Notes | ELISA: 1:40000Optimal dilutions should be determined experimentally by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 degrees Celcius. Product is stable for at least 1 year. |
| Storage Buffer | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
