Application
IHC analysis of Cav3.2 in frozen sections of mouse brain extract using| Product Name | Cav3.2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [S55-10] to Cav3.2This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE). [provided by RefSeq] |
| Immunogen | Fusion protein amino acids 1019-1293 (II-III loop) of human Cav3.2, accession number O95180 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | S55-10 |
| Host Species | Mouse |
| Tested Applications | ICC/IFIHC-FIPWB |
| We recommend a working dilution of 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF).: |
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| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Protein G |
| Gene Synonyms | EIG6 CACNA1HB Voltage dependent T type calcium channel alpha 1H CACNA 1H Cav T.2 CACNA1 HB Alpha13.2 Alpha1 3.2 Voltage dependent T type calcium channel alpha1H CACNA1H |
|---|---|
| Target | Cav3.2 |
| Molecular Weight(MW) | 260kDa (note) |
| Tissue Specificity | No cross-reactivity against Cav1.3 |
Application
IHC analysis of Cav3.2 in frozen sections of mouse brain extract using| Application Notes | We recommend a working dilution of 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF).: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20 C. Avoid repeated freeze-thaw cycles. |
| Storage Buffer | PBS pH7.4, 50% glycerol |
