Application
FACS ImageStaining of bovine peripheral platelets with Mouse anti-Bovine CD41Application
FACS ImageStaining of permeablised RBL-CCR5 transfectants following stimulation with PMA, with Mouse anti-Human CD195 (PHOSPHORYLATED AT SER337)| Product Name | CCR5 (phospho Ser337) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [V14/2] to CCR5 (phospho Ser337)This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gen |
| Immunogen | Synthetic phospho peptide corresponding to the C-Terminal region of human CCR5 conjugated to BSA. |
| Modification | p-Ser337 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | V14/2 |
| Host Species | Mouse |
| Tested Applications | ELISAFACSICC/IFWB |
| Flow Cytometry: 1/25 - 1/50: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | phospho CCR5 Ser337 Phospho CCR5 (pS337) CCCKR5 Phospho CCR5 (Ser337) CMKBR5 IDDM22 Phospho CCR5 (pSer337) phospho CCR5 S337 CCR5 phospho CD195 CKR5 CCR5 (Phospho S337) CC-CKR-5 CCR5 (Phospho Ser337) phospho Ser337 |
|---|---|
| Target | CD195 (phospho Ser337) |
Application
FACS ImageStaining of bovine peripheral platelets with Mouse anti-Bovine CD41
Application
FACS ImageStaining of permeablised RBL-CCR5 transfectants following stimulation with PMA, with Mouse anti-Human CD195 (PHOSPHORYLATED AT SER337)| Application Notes | Flow Cytometry: 1/25 - 1/50: |
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| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered saline containing 0.09% Sodium Azide |
