Application
IHC-P analysis of human lymph node tissue using CCR5 antibody.Application
WB analysis of THP-1 cell lysate using CCR5 antibody.| Product Name | CCR5 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to CCR5This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gen |
| Immunogen | Peptide corresponding to amino acids 6 to 20 of human CCR5. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| Western Blotting: Max Dilution 1/1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | chemokine (C-C motif) receptor 5 (gene/pseudogene) CCCKR5 CMKBR5 IDDM22 CD195 CKR5 CC-CKR-5 CKR-5 CCR-5 |
|---|---|
| Target | CCR5 |
| Tissue Specificity | This antibody recognizes the N-terminal region of the chemokine receptor CCR5. |
Application
IHC-P analysis of human lymph node tissue using CCR5 antibody.
Application
WB analysis of THP-1 cell lysate using CCR5 antibody.| Application Notes | Western Blotting: Max Dilution 1/1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered saline containing 0.02% Sodium Azide |
