Application
FACS ImageStaining of permeabilized resting RBL-CCR5 transfectants with Mouse anti-Human CD195 NON PHOSPHORYLATED| Product Name | CCR5 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [R-C10] to CCR5This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gen |
| Immunogen | Synthetic peptide corresponding to the C-Terminal region of human CCR5 conjugated to BSA. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | R-C10 |
| Host Species | Mouse |
| Tested Applications | ELISAFACSICC/IFWB |
| Flow Cytometry: 1/25 - 1/50: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CCCKR5 CMKBR5 IDDM22 CD195 CKR5 CC-CKR-5 CKR-5 CCR-5 |
|---|---|
| Target | CD195 (Non-Phosphorylated) |
| Tissue Specificity | This antibody is specific for human CCR5 (CD195). Clone R-C10 has not yet been tested for reactivity with human CD195 phosphorylated at other residues. |
Application
FACS ImageStaining of permeabilized resting RBL-CCR5 transfectants with Mouse anti-Human CD195 NON PHOSPHORYLATED| Application Notes | Flow Cytometry: 1/25 - 1/50: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered saline containing 0.09% Sodium Azide |
