Mouse monoclonal antibody [11G5a] to CD151The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
11G5a
Host Species
Mouse
Tested Applications
ELISAFACSIHC-FIHC-PIPWB
Flow Cytometry: 1/50 - 1/100:
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
MER2 GP27 SFA1 PETA-3 RAPH TSPAN24
Target
CD151
Tissue Specificity
This antibody recognizes the human CD151 cell surface antigen, also known as PETA-3.
Application
Application
FACS analysis of human peripheral blood platelets using CD151 antibody [11G5a].
Application Notes
Flow Cytometry: 1/50 - 1/100:
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.