Mouse monoclonal antibody [8S23] to CD252The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells. [provided by RefSeq, Jul 2008]
Immunogen
Human recombinant TNFSF4
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
8S23
Host Species
Mouse
Tested Applications
FACSIHCNeut
FC(1:50-100)|IHC (frozen)(1:20-200)|Neutralization of TNFSF4 bioactivity: