Rabbit Polyclonal antibody to CD32B (phospho Tyr292)The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CD32b. The exact sequence is proprietary.
Modification
p-Tyr292
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB: 1:500 - 1:1000:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
FCG2 CD32 IGFR2 CD32B FCGR2B Fc fragment of IgG low affinity IIb receptor (CD32) FCGR2
Target
CD32B (phospho Tyr292)
Tissue Specificity
Recognizes endogenous levels of CD32b (pY292) protein.
Application
Application
Western blot analysis of CD32b (pY292) expression in MCF7 pervanadate-treated (A); mouse liver (B); PC12 pervanadate-treated (C) whole cell lysates.
Application Notes
WB: 1:500 - 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles.
Storage Buffer
Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide.