Application
Western blot analysis of extracts from K562 cells treated with PMA using CD32 (Phospho-Tyr292) Antibody. The lane on the right is treated with the antigen-specific peptide.| Product Name | CD32 (phospho Tyr292) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CD32, FCG2, FCG2B,, LY-17, CDW32 |
| Product description | Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.1) Stuart S.G., EMBO J. 8:3657-3666(1989). |
| Immunogen | CD32 (phospho Tyr292) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 292 (I-T-Y (p)-S-L) derived from Human CD32. |
| Modification | p-Tyr292 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | FCGR2B |
|---|---|
| Alternative Names | CD32 FCG2 FCG2B LY-17 CDW32 |
| Molecular Weight(MW) | 32 kDa |
| Tissue Specificity | The antibody detects endogenous levels of CD32 only when phosphorylated at tyrosine 292. |
| Entrez Gene | 2213 |
|---|---|
| Protein Accession | NP_003992.3 |
Application
Western blot analysis of extracts from K562 cells treated with PMA using CD32 (Phospho-Tyr292) Antibody. The lane on the right is treated with the antigen-specific peptide.| Application Notes | Western Blot: 1:500~1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
