Application
ApplicationApplication
GPIIb antibody [MEM-06] imageApplication
Surface staining of human platelets with anti-human CD41 [MEM-06] (PE).| Product Name | CD41 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [MEM-06] to CD41Integrin alpha 2b (CD41) is a calcium-depedent, noncovalently associated heterodimer and contains a heavy chain (GPIIb-alpha) and a light chain (GPIIb-beta) linked by a single disulfied bond.T he integrin alpha 2B chain interacts with the integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major integrin on platelets and is important for platelet adhesion and aggregation. |
| Immunogen | Tissue / cell preparation (Human). (Leucocytes of patient suffering from LGL-type leukaemia). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | MEM-06 |
| Host Species | Mouse |
| Tested Applications | FACSWB |
| For FACS: Use at 2 µg/mL: |
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| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | CD41 CD41b GP2B GTA Integrin alpha 2b ITGA2B PGIIIb Platelet Fibrinogen Receptor Alpha Subunit Platelet glycoprotein IIb of IIb / IIIa complex Platelet Glycoprotein IIIb Platelet specific Antigen Bak |
|---|---|
| Target | CD41 |
| Tissue Specificity | This antibody reacts with CD41 antigen. |
Application
Application
Application
GPIIb antibody [MEM-06] image
Application
Surface staining of human platelets with anti-human CD41 [MEM-06] (PE).| Application Notes | For FACS: Use at 2 µg/mL: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate buffered saline pH 7.4 containing 15mM sodium azide |
