Mouse monoclonal antibody [GRP-P] to CD42aThis gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. [provided by RefSeq, Oct 2008]
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
GRP-P
Host Species
Mouse
Tested Applications
FACSIP
Flow Cytometry: 1/10 - 1/100 Optimal dilution / concentration should be determined by the end user.:
Species Reactivity
HumanDogMink
Concentration
1mg/ml
Target Information
Gene Synonyms
GPIX GP9
Target
CD42a
Tissue Specificity
This antibody recognizes human CD42a, also known as GP-IX.
Application
Application
FACS analysis of human peripheral blood platelets using CD42a antibody [GRP-P].
Application Notes
Flow Cytometry: 1/10 - 1/100 Optimal dilution / concentration should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.