| Product Name | CD45 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [IH1] to CD45The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognising a common epitope on all of the isoforms are termed CD45 whilst those recognising only individual isoforms are termed CD45RA or CD45RO etc. |
| Immunogen | Leukaemic lymphocytes from guinea pig |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Clone Number | IH1 |
| Host Species | Mouse |
| Tested Applications | ICC/IFIHC-FIP |
| For IF: Use at a concentration of 5-20μg/ml. For IP: Use at a concentration of 5-20μg/ml. Optimal dilutions/concentrations should be determined by the researcher.: |
|
| Species Reactivity | Human |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Anti-B220 Anti-CD 45 Anti-CD45 Anti-CD45 antigen Anti-GP180 Anti-L CA Anti-LCA Anti-LY5 Anti-Leukocyte common antigen Anti-PTPRC Anti-Protein tyrosine phosphatase receptor type C Anti-Protein tyrosine phosphatase receptor type c polypeptide Anti-SCID due t |
|---|---|
| Target | CD45 |
| Tissue Specificity | Detects all isoforms (180-220 kDa) |
| Light Chain Type | lambda |
| Positive Control | H201 |
|---|---|
| Application Notes | For IF: Use at a concentration of 5-20μg/ml. For IP: Use at a concentration of 5-20μg/ml. Optimal dilutions/concentrations should be determined by the researcher.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate-buffered saline, pH 7.2, containing no preservatives |
