Mouse monoclonal antibody [Bu14] to CD55This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF); binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
Bu14
Host Species
Mouse
Tested Applications
FACS
Flow Cytometry: Neat - 1/200 Optimal dilution / concentration should be determined by the end user.:
This antibody recognizes human CD55, also known as Decay Accelerating Factor (DAF).
Application
Application
FACS analysis of human peripheral blood monocytes using CD55 antibody [Bu14].
Application Notes
Flow Cytometry: Neat - 1/200 Optimal dilution / concentration should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.