Mouse monoclonal antibody [CL2/6] to CD62EThe protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq, Jul 2008]
Key Feature
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
CL2/6
Host Species
Mouse
Tested Applications
FACSICC/IFIHC-F
Flow Cytometry: Max Dilution 1/20:
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
LECAM2 ESEL ELAM ELAM1 SELE
Target
CD62e
Tissue Specificity
This antibody recognizes human CD62E.
Application Notes
Flow Cytometry: Max Dilution 1/20:
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.