| Product Name | CD62L antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [FMC46] to CD62LThe human CD62L is a 74-95 kD glycoprotein member of the selectin family of adhesion receptors. L-Selectin is comprised of an aminoterminal C-type lectin binding domain, an epidermal growth factor-like domain, two short consensus repeat (SCR) sequences homologous to those found in complement binding proteins, a short spacer region, a transmembrane region and a short cytoplasmic region. Human CD62L (L-Selectin) is constitutively expressed on all classes of leukocytes including lymphocytes (except a substantial population of memory T cells), monocytes and polymorphonuclear cells. It is expressed on bone marrow myeloid progenitor cells, erythroid precursor cells and some thymocytes. It is preferentially localized to the tips of lymphocytes and polymorphonuclear cells microvilli. Bioactive soluble L-Selectin derived from lymphocytes and neutrophils is present in normal and pathological biological fluids. |
| Immunogen | Human PHA-activated peripheral blood mononuclear cells. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | FMC46 |
| Host Species | Mouse |
| Tested Applications | FACSIHC-F |
| FACS:Use at an dependent assay. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Synonyms | SELL Leu-8 LSEL 6402 Lyam1 LNHR P14151 153240 LAM1 LECAM1 hLHRc LAM-1 TQ1 PLNHR CD62L Lyam-1 Leu8 Leu 8 LAM 1 Lyam 1 |
|---|---|
| Target | CD62L |
| Tissue Specificity | recognizes the human CD62L antigen expressed on neutrophils, monocytes, NK cells, B and certain T lymphocytes. |
| Cellular Localization | Cell Membrane |
| Positive Control | Tested with L1-2 cells. |
|---|---|
| Application Notes | FACS:Use at an dependent assay. Optimal dilutions/concentrations should be determined by the end user.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: None Constituents: 0.01M PBS (pH7.4) |
