Mouse monoclonal antibody [FMC46] to CD62LThis gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
Key Feature
Clonality
Monoclonal
Isotype
IgG2
Clone Number
FMC46
Host Species
Mouse
Tested Applications
FACSIHC-FIP
Flow Cytometry: 1/50 - 1/100 Optimal dilution / concentration should be determined by the end user.:
This antibody recognizes human CD62L, also known as L-selectin.
Application Notes
Flow Cytometry: 1/50 - 1/100 Optimal dilution / concentration should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.