Mouse Monoclonal antibody [AK4] to CD62PThis gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. [provided by RefSeq, Jul 2008]
Immunogen
Human platelets
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
AK4
Host Species
Mouse
Tested Applications
FACSICC/IFIPWBFunctional Assay
FACS: 1.5 ug/ml:
Species Reactivity
HumanPrimate
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Protein A
Target Information
Gene Synonyms
SELP GRMP selectin P (granule membrane protein 140kDa antigen CD62) LECAM3 CD62 PSEL GMP140 PADGEM