| Product Name | CD8 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [289-13804(UCH-T4(C3))] to CD8The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq] |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | 289-13804(UCH-T4(C3)) |
| Host Species | Mouse |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CD8B LYT3 Leu2 Ly3 MGC119115 |
|---|---|
| Target | CD8 |
| Tissue Specificity | CD8 |
| Light Chain Type | kappa |
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt, store at –20°C. Avoid multiple freeze/thaw cycles. |
| Storage Buffer | 10mM Phosphate, pH 7.4 containing 150mM Sodium chloride and 0.1% Sodium Azide |
