Application
IHC-Fr analysis of human tonsil tissue using CD8 antibody [LT8] (Azide free).| Product Name | CD8 antibody (Azide free) |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [LT8] to CD8The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq, May 2010] |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | LT8 |
| Host Species | Mouse |
| Tested Applications | BlockingFACSIHC-FIP |
| Flow Cytometry: 1/50 - 1/100 Optimal dilution / concentration should be determined by the end user.: |
|
| Species Reactivity | HumanChimpanzeeRhesus MonkeyCynomolgus Monkey |
| Concentration | 1mg/ml |
| Gene Synonyms | P37 LYT3 CD8B LY3 LEU2 CD8B1 |
|---|---|
| Target | CD8 |
| Tissue Specificity | This antibody recognizes human CD8. |
Application
IHC-Fr analysis of human tonsil tissue using CD8 antibody [LT8] (Azide free).| Application Notes | Flow Cytometry: 1/50 - 1/100 Optimal dilution / concentration should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C only. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered saline |
