Application
FACS ImageStaining of human peripheral blood monocytes with Mouse anti Human CD86:FITCApplication
FACS ImageStaining of human peripheral blood monocytes with Mouse anti Human CD86:RPE| Product Name | CD86 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [BU63] to CD86This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011] |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | BU63 |
| Host Species | Mouse |
| Tested Applications | FACSICC/IFIHC-FIP |
| Flow Cytometry: 1/20 - 1/100: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CD86 molecule B7-2 LAB72 B70 B7.2 CD28LG2 |
|---|---|
| Target | CD86 |
| Tissue Specificity | This antibody recognizes human CD86 also known as B7-2, a type I transmembrane protein expressed by monocytes and activated B cells (Engel et al. 1994). CD86 acts as a co-stimulaory molecule along with CD80 (Lanier et al. 1995) and is a ligand for CD28 an |
Application
FACS ImageStaining of human peripheral blood monocytes with Mouse anti Human CD86:FITC
Application
FACS ImageStaining of human peripheral blood monocytes with Mouse anti Human CD86:RPE| Application Notes | Flow Cytometry: 1/20 - 1/100: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered saline containing 0.09% Sodium Azide (NaN3) |
