Mouse monoclonal antibody [MIP8a] to CD89This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Immunogen
Recombinant soluble human Fc alpha R
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
MIP8a
Host Species
Mouse
Tested Applications
ELISAFACSIPWB
Flow Cytometry: 1/50 - 1/100 Optimal dilution / concentration should be determined by the end user.:
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
Fc fragment of IgA receptor for FCAR
Target
CD89
Tissue Specificity
This antibody recognizes human CD89.
Application
Application
FACS analysis of human peripheral blood granulocytes using CD89 antibody [MIP8a].
Application Notes
Flow Cytometry: 1/50 - 1/100 Optimal dilution / concentration should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.