Application
Western blot analysis of extracts of various cell lines, using CDK4 antibody.Application
Immunohistochemistry of paraffin-embedded human liver injury using CDK4 antibody at dilution of 1:100 (x400 lens).Application
Immunohistochemistry of paraffin-embedded rat kidney using CDK4 antibody at dilution of 1:100 (x400 lens).Application
Immunohistochemistry of paraffin-embedded rat liver using CDK4 antibody at dilution of 1:100 (x400 lens).Application
Immunohistochemistry of paraffin-embedded rat lung using CDK4 antibody at dilution of 1:100 (x400 lens).| Product Name | CDK4 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to CDK4The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [provided by RefSeq, Jul 2008] |
| Immunogen | Recombinant protein of human CDK4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCIHC-PWB |
| WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:20 - 1:100: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CMM3 PSK J3 cyclin-dependent kinase 4 |
|---|---|
| Target | CDK4 |
Application
Western blot analysis of extracts of various cell lines, using CDK4 antibody.
Application
Immunohistochemistry of paraffin-embedded human liver injury using CDK4 antibody at dilution of 1:100 (x400 lens).
Application
Immunohistochemistry of paraffin-embedded rat kidney using CDK4 antibody at dilution of 1:100 (x400 lens).
Application
Immunohistochemistry of paraffin-embedded rat liver using CDK4 antibody at dilution of 1:100 (x400 lens).
Application
Immunohistochemistry of paraffin-embedded rat lung using CDK4 antibody at dilution of 1:100 (x400 lens).| Application Notes | WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:20 - 1:100: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
