Application
IHC analysis of rat lung with (left) or without (right) CFTR antibody.Application
WB analysis of rat lung lysates using CFTR antibody at a dilution of 1:200 in the (1) absence or (2) presence of blocking peptide.| Product Name | CFTR antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to CFTRThis gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily that is involved in multi-drug resistance. The encoded protein functions as a chloride channel and controls the regulation of other transport pathways. Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens. Alternatively spliced transcript variants have been described, many of which result from mutations in this gene. [provided by RefSeq, Jul 2008] |
| Immunogen | Peptide (C)KEETEEEVQDTRL, corresponding to amino acid residues 1468-1480 of human CFTR (Accession #P13569). Cytoplasmic, C-terminal part. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| IHC:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C member 7) TNR-CFTR CF MRP7 CFTR/MRP ABC35 ABCC7 dJ760C5.1 |
|---|---|
| Target | CFTR |
Application
IHC analysis of rat lung with (left) or without (right) CFTR antibody.
Application
WB analysis of rat lung lysates using CFTR antibody at a dilution of 1:200 in the (1) absence or (2) presence of blocking peptide.| Application Notes | IHC:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20oC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Reconstituted powder containsA?phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3. |
