SDS-PAGE
SDS-PAGE for Anti-Human CFTR Monoclonal Antibody| Product Name | Anti-CFTR Monoclonal Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Purity >95% as determined by SDS-PAGE.
|
| Immunogen | E. coli - derived recombinant human CFTR (Ile1203-Ser1426). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:200-1:2000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A/G |
| Gene Symbol | CFTR |
|---|---|
| Gene Synonyms | CF MRP7 ABC35 ABCC7 CFTR/MRP TNR-CFTR dJ760C5.1 |
| Gene Full Name | CF transmembrane conductance regulator |
| Gene Summary | This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. The encoded protein functions as a chloride channel, making it unique among members of this protein family, and controls ion and water secretion and absorption in epithelial tissues. Channel activation is mediated by cycles of regulatory domain phosphorylation, ATP-binding by the nucleotide-binding domains, and ATP hydrolysis. Mutations in this gene cause cystic fibrosis, the most common lethal genetic disorder in populations of Northern European descent. The most frequently occurring mutation in cystic fibrosis, DeltaF508, results in impaired folding and trafficking of the encoded protein. Multiple pseudogenes have been identified in the human genome. [provided by RefSeq, Aug 2017] |
| Cellular Localization | Cell membrane,Endoplasmic reticulum,Endosome,Membrane,Nucleus |
SDS-PAGE
SDS-PAGE for Anti-Human CFTR Monoclonal Antibody| Application Notes | WB:1:200-1:2000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
