Mouse Monoclonal antibody [5F1-A11-C9] to CHD4The product of this gene belongs to the SNF2/RAD54 helicase family.It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression.Patients with dermatomyositis develop antibodies against this protein.[provided by RefSeq,Jul 2008]
Immunogen
Purified recombinant human CHD4 protein fragments expressed in E.coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG2
Clone Number
5F1-A11-C9
Host Species
Mouse
Tested Applications
WB
WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
Mi-2b chromodomain helicase DNA binding protein 4 Mi2-BETA
Target
CHD4
Molecular Weight(MW)
260kDa (note)
Cellular Localization
Nucleus. Cytoplasm cytoskeleton centrosome.
Application
Application
WB analysis of indicated lysates using CHD4 antibody at a dilution of 1:1,000.
Application Notes
WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified mouse monoclonal in PBS(pH 7.4)containing with 0.02% sodium azide,50% glycerol.