Western blot analysis using anti-CHIT1 monoclonal antibody against truncated Trx-CHIT1 recombinant protein(1) and truncated CHIT1(aa22-466)-hIgGFc transfected CHO-K1 cell lysate(2).
Mouse monoclonal antibody [1D9G2,1D9G4,2B4G3] to CHIT1Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2012]
Immunogen
The immunogen corresponding to a region within amino acids 22 and 137 of CHIT1 expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1D9G2,1D9G4,2B4G3
Host Species
Mouse
Tested Applications
ELISAWB
ELISA: 1/10000.:
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
CHIT CHI3 CHITD
Target
CHIT1
Application
Application
Western blot analysis using anti-CHIT1 monoclonal antibody against truncated Trx-CHIT1 recombinant protein(1) and truncated CHIT1(aa22-466)-hIgGFc transfected CHO-K1 cell lysate(2).
Application Notes
ELISA: 1/10000.:
Additional Information
Form
Liquid
Storage Instructions
Store at 4℃, for long term storage, store at -20℃.