Mouse polyclonal antibody to Chk2CHK2 controls cell cycle checkpoint and may participate in transduction of the DNA damage and replicational stress signals. CHK2 belongs to the Ser/Thr protein kinase family and its kinase actibity is up-regulated by autophosphorylation, It is phosphorylated rapidly in response to DNA damage and to replication block.
Key Feature
Clonality
Monoclonal
Host Species
Mouse
Tested Applications
WB
For WB: Use at a dilution of 1:1,000. Optimal dilutions/concentrations should be determined by the researcher.