Rabbit polyclonal to Chromogranin AChromogranin A (a protein of 439 amino acid which is encoded on chromosome 14) is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, phenochromocytomas, paragangliomas, and other neuroendocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.
Immunogen
Recombinant protein encoding C-terminal Chromogranin A
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCIHC-P
For IHC-P: Use at a dilution of 1:400 for 10 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Concentration
0.2mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
118910, Chromogranin A, P10645, CGA, 1113, CHGA
Target
Chromogranin A
Cellular Localization
Cytoplasmic
Application
Application
Application
Application
Human Pancreas stained with anti-Chromogranin A antibody
Application
Immunohistochemical staining of human pancreas with
Positive Control
Pancreas
Application Notes
For IHC-P: Use at a dilution of 1:400 for 10 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution, aliquot and store at 4°C.
Storage Buffer
Phosphate-buffered saline, pH 7.4, containing BSA and sodium azide