Monoclonal Mouse Antibody to Human Chromogranin AChromogranin A is a 439 amino acid protein present in secretory granules of a wide variety of endocrine cells and neurons. A positive staining is seen in the secretory granules of parathyroid, adrenal medulla, anterior pituitary gland and Langerhans isletsof pancreas. This antibody stains a variety of neuroendocrine tumors.
Immunogen
Purified C-terminal half of chromogranin A from urine of patients with carcinoid syndrome.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
LK2H10
Host Species
Mouse
Tested Applications
IHC-P
This antibody has been pretitered and quality controlled to work on formalin-fixed paraffin-embedded as well as acetone fixed cryostat tissue sections. No further titration is required. We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user. Suitable for formalin/paraffin tissues.
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
118910, Chromogranin A, P10645, CGA, 1113, CHGA
Target
Chromogranin A
Cellular Localization
Cytoplasmic
Light Chain Type
kappa
Positive Control
Pancreas
Application Notes
This antibody has been pretitered and quality controlled to work on formalin-fixed paraffin-embedded as well as acetone fixed cryostat tissue sections. No further titration is required. We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user. Suitable for formalin/paraffin tissues.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution, aliquot and store at 4°C.