Mouse monoclonal antibody [PHE5] to Chromogranin AThe protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown. [provided by RefSeq, Jul 2008]
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
PHE5
Host Species
Mouse
Tested Applications
IHC-PWB
Immunohistology - Paraffin: 1/250 - 1/1000 Optimal dilution / concentration should be determined by the end user.
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
CGA , CHGA , chromogranin A (parathyroid secretory protein 1)
Target
Chromogranin A
Tissue Specificity
This antibody recognizes chromogranin A (CgA).
Application
Application
IHC-P analysis of human pancreas tissue using Chromogranin A antibody [PHE5].
Application Notes
Immunohistology - Paraffin: 1/250 - 1/1000 Optimal dilution / concentration should be determined by the end user.
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.