Application
Immunohistochemical analysis of paraffin-embedded human brain tissue using Claudin 5 (Phospho-Tyr217) antibody (left) or the same antibody preincubated with blocking peptide (right).| Product Name | Claudin 5 (phospho Tyr217) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Claudin 5 (phospho Tyr217)This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2008] |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 217 (K-K-N-Y(p)-V) derived from Human Claudin 5. |
| Modification | p-Tyr217 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-P |
| IHC: 1:50 - 1:100: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | CLDN5 claudin 5 BEC1 TMVCF CPETRL1 AWAL |
|---|---|
| Target | Claudin 5 (phospho Tyr217) |
| Tissue Specificity | The antibody detects endogenous levels of Claudin 5 only when phosphorylated at tyrosine 217. |
Application
Immunohistochemical analysis of paraffin-embedded human brain tissue using Claudin 5 (Phospho-Tyr217) antibody (left) or the same antibody preincubated with blocking peptide (right).| Application Notes | IHC: 1:50 - 1:100: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20˚C/1 year |
| Storage Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
