| Product Name | CLN-2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [9V1] to CLN-2This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq, Jul 2008] |
| Immunogen | Human recombinant CLN-2 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | 9V1 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB(1:500-1000): |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | TPP-1 TPP1 LPIC tripeptidyl peptidase I GIG1 CLN2 |
|---|---|
| Target | CLN-2 |
| Tissue Specificity | This antibody was selected for its ability to detect human CLN-2. |
| Application Notes | WB(1:500-1000): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
