Mouse monoclonal antibody [5131] to Clostridium botulinum D ToxoidThe protein encoded by this gene contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to form protein complexes and function as transcription repressors. This protein has been shown to interact with some PcG proteins and act as a transcription repressor. The activity of this protein is found to be regulated by cell cycle dependent phosphorylation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
Immunogen
Tissue / cell preparation.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
5131
Host Species
Mouse
Tested Applications
ELISAICC/IFIHC
ELISA: Use at a dilution of 1/20 - 1/200. ICC/IF: Use at a dilution of 1/10 - 1/50. IHC: Use at a dilution of 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.:
Concentration
1mg/ml
Target Information
Gene Synonyms
BoNT/D Bontoxilysin D BOTD Botulinum neurotoxin type D
Target
Clostridium botulinum D Toxoid
Tissue Specificity
is specific for the toxin / toxoid D of C botulinum.
Cellular Localization
Secreted
Application Notes
ELISA: Use at a dilution of 1/20 - 1/200. ICC/IF: Use at a dilution of 1/10 - 1/50. IHC: Use at a dilution of 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.